“School of Nano-Sciences”

Back to Papers Home
Back to Papers of School of Nano-Sciences

Paper   IPM / Nano-Sciences / 17477
School of Nano Science
  Title:   Detection of intralayer alignment in multicomponent lipids by dynamic speckle pattern analysis
  Author(s): 
1.  Majid Panahi
2.  Vahideh Farzam Rad
3.  Shiva Sasan
4.  Ramin Jamali
5.  Ali-Reza Moradi
6.  Ahmad Darudi
  Status:   Published
  Journal: Journal of Biophotonics
  Vol.:  15
  Year:  2022
  Supported by:  IPM
  Abstract:
Multicomponent mixtures of bilayer lipids, thanks to the coexistence of liquid-crystalline phases in their structures, may be used in the development of functional membranes. In such membranes interlayer ordering distributes across membrane lamellae, resulting in long-range alignment of phase-separated domains. In this paper, we explore the dynamics of this phenomenon by laser speckle pattern analysis. We show that cholesterol content decreases the activity, and the rate of the domains size development is related to the change of physical roughness of the multicomponent lipid mixture. Our results are in agreement with the previous experimental reports. However, our experimental procedure is an easy-to-implement and effective methodology.

Download TeX format
back to top
scroll left or right