“School of Nano-Sciences”
Back to Papers HomeBack to Papers of School of Nano-Sciences
| Paper IPM / Nano-Sciences / 18347 |
|
||||||||||||
| Abstract: | |||||||||||||
|
Modeling the blood-brain barrier has long been a challenge for pharmacological studies. Up to the present, numerous attempts have been devoted to recapitulating the endothelial barrier in vitro to assess drug delivery vehicles' efficiency for brain disorders. In the current work, we presented a new approach for analyzing the morphometric parameters of the cells of an insert co-culture blood-brain barrier model using rat brain astrocytes, rat brain microvascular endothelial cells, and rat brain pericytes. This analytical approach could aid in getting further information on drug trafficking through the blood-brain barrier and its impact on the brain indirectly.
Download TeX format |
|||||||||||||
| back to top | |||||||||||||
